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Mechanism of Action of Pilocarpine

Mechanism of action of Pilocarpine

Introduction Pilocarpine is a direct-acting muscarinic receptor agonist used primarily in glaucoma and xerostomia. It mimics the action of acetylcholine at muscarinic receptors, producing parasympathetic effects. In ophthalmology, pilocarpine lowers intraocular pressure by increasing aqueous humor outflow. It is also used to stimulate salivary secretion in conditions such as Sjögren syndrome. Mechanism of Action (Step-wise) … Read more

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