Mechanism of Action of Tocilizumab
Introduction Tocilizumab is a humanized monoclonal antibody targeting the interleukin-6 receptor (IL-6R). It is approved for rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), giant cell arteritis (GCA), Castleman disease, cytokine release syndrome (CRS), and spondyloarthritis-associated uveitis. By blocking IL-6 signaling, it dampens inflammation in various autoimmune and inflammatory diseases. Step-by-Step Mechanism of Action Pharmacokinetic Parameters … Read more