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Mechanism of Action of Azathioprine

MOA of Azathioprine

Introduction Azathioprine is an immunosuppressive and cytotoxic drug primarily used in organ transplantation, autoimmune disorders, and inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus (SLE), and inflammatory bowel disease (IBD). Mechanism of Action of Azathioprine involves suppression of DNA synthesis and lymphocyte proliferation by interfering with purine metabolism. It acts as a prodrug of … Read more

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