carbimazole

Introduction Carbimazole is a thiourea-derived antithyroid drug used primarily in the management of hyperthyroidism, especially Graves’ disease, toxic multinodular goiter, and thyroid storm (as adjunct therapy). After oral administration, carbimazole is rapidly converted to its active metabolite methimazole, which exerts the therapeutic effects. The Mechanism of Action of Carbimazole involves suppression of thyroid hormone synthesis … Read more