aminoglycosides

Introduction Amikacin is a broad-spectrum aminoglycoside antibiotic primarily used to treat severe Gram-negative bacterial infections, including those resistant to other aminoglycosides. Mechanism of Action of Amikacin involves irreversible inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit, leading to misreading of mRNA and defective protein formation. Because of its stability against many … Read more