Mechanism of Action of Pioglitazone
Introduction Pioglitazone is an oral antidiabetic agent belonging to the thiazolidinedione (TZD) class. It is used primarily in the management of type 2 diabetes mellitus by improving insulin sensitivity. Unlike insulin secretagogues, pioglitazone does not increase insulin secretion but acts on peripheral tissues to enhance insulin action. Its unique mechanism involves modulation of gene expression … Read more