Introduction Haloperidol is a first generation (typical) antipsychotic belonging to the butyrophenone class. It is widely used in the treatment of schizophrenia, acute psychosis, delirium, and severe agitation. Haloperidol primarily works by blocking dopamine receptors in the central nervous system, particularly in the mesolimbic pathway. Because excessive dopamine activity in the mesolimbic pathway is associated … Read more
Introduction Aripiprazole is a third-generation atypical antipsychotic approved for treating schizophrenia, bipolar disorder, depression (as an adjunct), Tourette’s syndrome, and irritability in autism. It is pharmacologically unique for its role as a partial agonist at dopamine D₂ and serotonin 5‑HT₁A receptors, and as an antagonist at serotonin 5‑HT₂A receptors, allowing it to modulate neurotransmission rather … Read more
Introduction Aripiprazole is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, major depressive disorder (as adjunct), irritability in autism, and Tourette’s syndrome. Its unique action as a dopamine D₂ partial agonist, along with effects on serotonin receptors, sets it apart from other agents, providing antipsychotic efficacy with a lower risk of certain side effects. … Read more
