Mechanism of Action of Palbociclib
Introduction Palbociclib is an oral targeted anticancer drug marketed under the brand name Ibrance. Pharmacologically, palbociclib is a cyclin-dependent kinase 4 and 6 inhibitor, commonly called a CDK4/6 inhibitor. Cell-cycle control is one of the most important concepts in cancer pharmacology. Normal cells divide only after receiving controlled growth signals. Cancer cells often escape these … Read more
