Mechanism of Action of Nitrofurantoin
Introduction Nitrofurantoin is a nitrofuran antibacterial drug used mainly for uncomplicated lower urinary tract infections. It is especially useful because it achieves therapeutic antibacterial activity in urine and acts through multiple intracellular targets within bacteria. Unlike many antibiotics that inhibit a single enzyme or pathway, nitrofurantoin is reduced inside bacterial cells to highly reactive intermediates … Read more