Mechanism of Action of Midodrine
Introduction Midodrine is a prodrug used in the treatment of symptomatic orthostatic hypotension. It works by increasing vascular tone through selective stimulation of alpha-1 adrenergic receptors after being metabolized into its active form, desglymidodrine. Step-by-Step Mechanism of Action Pharmacokinetic Parameters Parameter Value Route Oral Bioavailability Approximately 93% Active Form Desglymidodrine Tmax 1–2 hours Half-life 3–4 … Read more