Mechanism of Action of Losartan
Introduction Losartan is an angiotensin II receptor blocker (ARB) widely used in the management of hypertension, heart failure, and diabetic nephropathy. Unlike ACE inhibitors, losartan directly blocks the effects of angiotensin II at its receptor rather than inhibiting its formation. This results in vasodilation, reduced aldosterone secretion, and decreased blood pressure without significantly affecting bradykinin … Read more