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Mechanism of Action of Loratadine

Loratadine pharmacology

Introduction Loratadine is a second-generation antihistamine widely used in the treatment of allergic conditions such as allergic rhinitis and urticaria. It selectively antagonizes peripheral histamine H1 receptors, thereby reducing allergic symptoms without causing significant sedation. Compared to first-generation antihistamines, loratadine has minimal penetration into the central nervous system, making it a preferred choice for daytime … Read more

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