GLP-1 - Pharmacy Freak

Mechanism of Action of Trulicity

July 21, 2026 Harsh Singh Rajput

Introduction Trulicity is the brand name of dulaglutide, a once-weekly injectable antidiabetic medicine used in type 2 diabetes mellitus. Pharmacologically, dulaglutide is a glucagon-like peptide-1 receptor agonist, commonly called a GLP-1 receptor agonist. GLP-1 is an incretin hormone released from intestinal L-cells after food intake. It helps regulate blood glucose by increasing insulin secretion, decreasing … Read more

Mechanism of Action of GLP-1 (Glucagon-Like Peptide-1)

April 10, 2026July 11, 2025 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Glucagon-like peptide-1 (GLP-1) is an endogenous incretin hormone secreted from the L-cells of the distal ileum and colon in response to food intake. It plays a critical role in regulating glucose homeostasis and energy balance. GLP-1 acts through specific receptors found in the pancreas, gastrointestinal tract, and central nervous system to modulate insulin secretion, … Read more