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Mechanism of Action of Racecadotril

MOA of Racecadotril

Introduction Racecadotril is an antidiarrheal drug used mainly in acute secretory diarrhea. Unlike opioid-based antidiarrheal agents, it does not significantly reduce intestinal motility. Racecadotril acts by inhibiting enkephalinase, thereby enhancing endogenous enkephalin activity in the gastrointestinal tract and reducing excessive intestinal secretion. Mechanism of Action (Step-wise) A key exam point is that racecadotril inhibits enkephalinase, … Read more

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