Mechanism of Action of Cytarabine
Introduction Cytarabine (also known as cytosine arabinoside or Ara-C) is a pyrimidine antimetabolite chemotherapeutic agent primarily used in the treatment of acute leukemias, especially acute myelogenous leukemia (AML). It is a cell cycle–specific drug, acting predominantly during the S-phase of the cell cycle. Cytarabine is a cornerstone drug in hematologic malignancies and is a high-yield … Read more