Mechanism of Action of Cyclophosphamide
Introduction Cyclophosphamide is a nitrogen mustard–derived alkylating agent widely used in oncology and immunosuppressive therapy. It is classified as a cell cycle–nonspecific cytotoxic drug and is used in the treatment of a broad spectrum of malignancies, as well as autoimmune and inflammatory disorders. Cyclophosphamide is a prodrug that requires hepatic activation, and its DNA-alkylating mechanism … Read more