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Mechanism of Action of Capecitabine

Introduction Capecitabine is an oral prodrug of 5-fluorouracil (5-FU) widely used in the treatment of breast cancer, colorectal cancer, and gastric cancers. Designed for tumor-selective activation, it delivers higher concentrations of active 5-FU to tumor cells while reducing systemic toxicity. The Mechanism of Action of Capecitabine centers on its stepwise conversion into 5-FU inside tumor … Read more

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