Mechanism of Action of Propylthiouracil
Introduction Propylthiouracil (PTU) is an antithyroid drug used in the treatment of hyperthyroidism and thyrotoxicosis, especially Graves disease. It belongs to the thioamide class and works by inhibiting thyroid hormone synthesis. PTU also decreases peripheral conversion of thyroxine (T4) to triiodothyronine (T3), making it particularly useful in thyroid storm. Mechanism of Action (Step-wise) A key … Read more