Mechanism of Action of Brimonidine
Introduction Brimonidine is a selective alpha-2 adrenergic receptor agonist primarily used in the management of open-angle glaucoma and ocular hypertension. It is also used topically for facial erythema in rosacea. By activating alpha-2 receptors, brimonidine reduces aqueous humor production and enhances uveoscleral outflow, leading to decreased intraocular pressure (IOP). Its dual mechanism, neuroprotective potential, and … Read more