Mechanism of Action of Physostigmine
Introduction Physostigmine is a reversible acetylcholinesterase inhibitor that increases acetylcholine levels at cholinergic synapses. Unlike quaternary ammonium anticholinesterases, physostigmine is a tertiary amine and can cross the blood-brain barrier, allowing central nervous system effects. It is commonly used in the treatment of anticholinergic toxicity. Mechanism of Action (Step-wise) A key exam point is that physostigmine … Read more