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Mechanism of Action of Romosozumab

Mechanism of Action of Romosozumab

Introduction Romosozumab is a humanized monoclonal antibody used for the treatment of osteoporosis in postmenopausal women who are at high risk of fracture. It is marketed under the brand name Evenity. Pharmacologically, romosozumab belongs to the sclerostin inhibitor class and is considered an anabolic bone-forming therapy with an additional antiresorptive effect. Osteoporosis is characterized by … Read more

Mechanism of Action of Teriparatide

mechanism of action of teriparatide

Introduction Teriparatide is a recombinant form of the first 34 amino acids of human parathyroid hormone (PTH 1-34), which represents the biologically active portion of the hormone. It is used primarily as an anabolic agent in the treatment of osteoporosis. Teriparatide is unique among osteoporosis therapies because it stimulates new bone formation rather than merely … Read more

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