Mechanism of Action of Alpelisib
Introduction Alpelisib is an oral targeted anticancer drug that belongs to the class of phosphatidylinositol-3-kinase inhibitors. It is mainly known as a selective PI3K alpha inhibitor and is used in diseases driven by activating mutations in the PIK3CA gene. In oncology, alpelisib is used in combination with fulvestrant for patients with hormone receptor-positive, HER2-negative, PIK3CA-mutated … Read more