Mechanism of Action of Abemaciclib
Introduction Abemaciclib is an oral targeted anticancer drug used mainly in hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer. It is marketed under the brand name Verzenio. Pharmacologically, abemaciclib belongs to the cyclin-dependent kinase 4 and 6 inhibitor class, commonly abbreviated as CDK4/6 inhibitors. CDK4 and CDK6 are important enzymes involved in cell-cycle … Read more