Mechanism of Action of Tafamidis
Introduction Tafamidis is an oral disease-modifying drug used for transthyretin amyloid cardiomyopathy, commonly abbreviated as ATTR-CM. It is marketed under the brand names Vyndaqel and Vyndamax. Pharmacologically, tafamidis is a transthyretin stabilizer. Transthyretin, or TTR, is a transport protein mainly produced by the liver. It normally circulates as a tetramer, meaning it is made of … Read more