Mechanism of Action of Fostamatinib

Introduction Fostamatinib is an oral targeted drug marketed under the brand name Tavalisse. Pharmacologically, fostamatinib is a spleen tyrosine kinase inhibitor, commonly called a SYK inhibitor. Immune thrombocytopenia, or ITP, is an autoimmune bleeding disorder in which platelets are destroyed faster than they can be replaced. In chronic ITP, autoantibodies bind to platelets and mark … Read more