Mechanism of Action of Azole Antifungal
Introduction Azoles are a major class of antifungal drugs widely used for the treatment of systemic and superficial fungal infections. They include imidazoles (e.g., ketoconazole, clotrimazole, miconazole) and triazoles (e.g., fluconazole, itraconazole, voriconazole, posaconazole). Mechanism of Action of Azole Antifungal Drugs centers on the inhibition of fungal ergosterol synthesis, an essential component of the fungal … Read more