Mechanism of Action of H2 Antagonists
Introduction H2 antagonists, also called H2 receptor blockers, are drugs used to reduce gastric acid secretion in conditions such as peptic ulcer disease, gastroesophageal reflux disease (GERD), and Zollinger–Ellison syndrome. These drugs block histamine H2 receptors located on gastric parietal cells, thereby inhibiting acid production. Common H2 antagonists include cimetidine, ranitidine, famotidine, and nizatidine. By … Read more