Pharmacy Freak Editorial Team

Pellets are small, free-flowing, spherical agglomerates used in multiparticulate drug delivery to improve flow, content uniformity, taste masking, and modified or sustained release. Key pelletization techniques include extrusion-spheronization, layer coating, and fluid-bed granulation; common excipients are microcrystalline cellulose, povidone, HPMC and ethylcellulose for release control. Critical attributes—particle size distribution, sphericity, porosity, friability and coating integrity—govern … Read more

Introduction: Soft gelatin capsules (softgels) are versatile oral dosage forms widely used in B. Pharm curricula and industry for delivering lipophilic and liquid drugs. They combine a gelatin-plasticizer shell with an oil-based or semi-solid fill to enhance solubility, bioavailability, and patient compliance. Key topics include shell composition, plasticizers, filling systems (rotary die, plate processes), stability … Read more

Packing, storage and stability testing of capsules covers critical concepts B.Pharm students must master to ensure capsule quality, efficacy and shelf life. This topic explores packaging materials (PVC, PVDC, aluminum, glass, HDPE), capsule types (gelatin, HPMC), moisture and temperature effects, desiccants, barrier properties, and regulatory stability requirements (ICH Q1A, Q1B). It also addresses stability study … Read more

Introduction Soft gelatin capsules are a common oral dosage form that require rigorous in-process and final quality control tests to ensure safety, potency, and performance. Key tests include fill weight determination, uniformity of dosage units, dissolution, assay (HPLC), moisture content (Karl Fischer), leak or seal integrity, shell hardness/elasticity, microbial limits, and stability. Understanding critical quality … Read more

Soft gelatin capsules (softgels) are versatile single-unit dosage forms with a soft, elastic gelatin shell encapsulating liquid, semi-solid or suspension fills. B.Pharm students must grasp formulation factors such as gelatin type, bloom strength, plasticizers (glycerin, sorbitol), moisture content, and fill compatibility, plus key manufacturing methods like rotary-die and plate processes. Critical quality attributes include seal … Read more

Introduction Base adsorption and minim/gram factors are key topics in pharmaceutics, linking surface chemistry with dosage calculation and drug formulation. This introduction covers adsorption mechanisms, isotherms (Langmuir, Freundlich), adsorption capacity (mg/g), kinetics, thermodynamics, and practical minim/gram considerations for measuring liquid volumes relative to powder mass. Understanding parameters such as Qe, Qmax, adsorption coefficient, contact time, … Read more

Understanding the Size of Soft Gelatin Capsules MCQs With Answer is essential for B.Pharm students focusing on dosage form design and pharmaceutical technology. Capsule size determines fill volume, drug content, dissolution rate, patient acceptability, packaging efficiency, and manufacturing parameters. Mastery of size codes, fill-volume calculations, density factors, shell composition, sealing integrity, and relevant USP/ICH tests … Read more

Introduction: Soft gelatin capsules are an important dosage form in B. Pharm curricula, focusing on capsule content, shell composition, formulation strategies, and stability. This topic covers fill materials (oils, solutions, suspensions), excipients (plasticizers, antioxidants, surfactants), shell ingredients (gelatin, plasticizers, colorants), manufacturing techniques (rotary die, dip-molding), and quality control (content uniformity, dissolution, leak testing). Understanding interactions, … Read more