Mechanism of Action of Upadacitinib

Introduction Upadacitinib is an oral Janus kinase inhibitor used in several immune-mediated inflammatory diseases. It is marketed under the brand name Rinvoq and is commonly classified as a selective JAK1 inhibitor, although it can affect other JAK enzymes at higher concentrations. Upadacitinib is used in conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic … Read more