Mechanism of Action of Leuprolide (Lupron)
Introduction Leuprolide is a synthetic gonadotropin-releasing hormone (GnRH) agonist used in conditions like prostate cancer, endometriosis, uterine fibroids, and central precocious puberty. Initially, it stimulates the pituitary gland, but with continuous use, it leads to receptor desensitization, suppressing gonadotropins and resulting in decreased sex hormone levels. Step-by-Step Mechanism of Action Pharmacokinetic Parameters Parameter Value Route … Read more