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Mechanism of Action of Hydroxychloroquine

Mechanism of Action of Hydroxychloroquine

Introduction Hydroxychloroquine is an antimalarial drug that also possesses significant immunomodulatory and anti-inflammatory properties. It is widely used in the treatment of malaria as well as autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis. Hydroxychloroquine acts primarily by interfering with lysosomal activity and antigen presentation in immune cells. It also affects Toll-like … Read more

Mechanism of Action of Chloroquine

MOA of Chloroquine

Introduction Chloroquine is a 4-aminoquinoline antimalarial drug historically used for the treatment and prophylaxis of Plasmodium falciparum, P. vivax, P. malariae, and P. ovale infections. Although resistance limits its use in many regions, chloroquine remains essential for sensitive strains and for autoimmune diseases such as rheumatoid arthritis and lupus. The Mechanism of Action of Chloroquine … Read more

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