Sodium Bicarbonate Bolus and Infusion Calculator (TCA toxicity)
About This Topic The Sodium Bicarbonate Bolus and Infusion calculator provides dosing support for managing cardiotoxicity associated with tricyclic antidepressant (TCA) overdose. Sodium bicarbonate is the primary antidote for TCA-induced QRS prolongation and ventricular dysrhythmias. It works by increasing extracellular sodium to overcome sodium channel blockade and by alkalinizing the serum, which decreases the binding … Read more
