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Mechanism of Action of Terlipressin

mechanism of action of terlipressin

Introduction Terlipressin is a synthetic vasopressin analogue and prodrug of lysine-vasopressin, primarily used to manage acute variceal bleeding and hepatorenal syndrome (HRS) in patients with advanced liver disease. It exerts selective vasoconstrictive effects through vasopressin V1 receptors, targeting the splanchnic circulation to improve effective arterial blood volume and renal perfusion. Mechanism of Action (Step-wise) 1. … Read more

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