Mechanism of Action of Defibrotide
Introduction Defibrotide is an intravenous drug marketed under the brand name Defitelio. Pharmacologically, defibrotide sodium is an oligonucleotide mixture with profibrinolytic, endothelial-protective, and antithrombotic-regulating properties. Defitelio is indicated for the treatment of adult and pediatric patients with hepatic veno-occlusive disease, also called VOD or sinusoidal obstruction syndrome, with renal or pulmonary dysfunction after hematopoietic stem-cell … Read more