Mechanism of Action of Primidone
Introduction Primidone is an antiepileptic drug used in the treatment of generalized tonic-clonic seizures, focal seizures, and essential tremor. It is structurally related to barbiturates and is metabolized into active metabolites including phenobarbital and phenylethylmalonamide (PEMA). Primidone reduces neuronal excitability and suppresses abnormal electrical activity in the brain. Mechanism of Action (Step-wise) A key exam … Read more