Mechanism of Action of Pramipexole
Introduction Pramipexole is a dopamine agonist primarily used in the treatment of Parkinson disease and restless legs syndrome (RLS). It directly stimulates dopamine receptors in the brain, helping compensate for dopamine deficiency in the nigrostriatal pathway. Compared to levodopa, pramipexole has a lower risk of motor fluctuations early in therapy but may produce behavioral adverse … Read more