Mechanism of Action of Tadalafil
Introduction Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor used primarily for erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension (PAH). It enhances the effects of nitric oxide-mediated vasodilation by preventing degradation of cyclic guanosine monophosphate (cGMP). Tadalafil is distinguished from other PDE5 inhibitors by its long duration of action, earning it … Read more