Mechanism of Action of Chlorpromazine
Introduction Chlorpromazine is a first-generation (typical) antipsychotic, belonging to the phenothiazine class. It is used for schizophrenia, acute psychosis, bipolar mania, severe agitation, intractable hiccups, nausea, and tetanus-associated agitation. The Mechanism of Action of Chlorpromazine centers on dopamine D2 receptor antagonism in the mesolimbic system, along with additional blockade of histamine, muscarinic, and alpha-1 adrenergic … Read more