Mechanism of Action of Vyndamax
Introduction Vyndamax is the brand name of tafamidis, an oral drug used in transthyretin amyloid cardiomyopathy, commonly called ATTR-CM. Pharmacologically, tafamidis is a selective stabilizer of transthyretin, or TTR. ATTR-CM occurs when transthyretin protein becomes unstable, dissociates from its normal tetrameric structure into monomers, misfolds, and forms amyloid fibrils. These amyloid deposits can accumulate in … Read more