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Mechanism of Action of Sulfonylureas

MOA of Sulfonylureas

Introduction Sulfonylureas are oral antidiabetic drugs used primarily in the treatment of type 2 diabetes mellitus. They lower blood glucose levels by stimulating insulin secretion from pancreatic β-cells. Common sulfonylureas include glibenclamide (glyburide), glipizide, gliclazide, and glimepiride. These drugs are effective only when functional pancreatic β-cells are present. Mechanism of Action (Step-wise) A key exam … Read more

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