antimetabolites

Introduction 5-Fluorouracil (5-FU) is an antimetabolite chemotherapeutic drug used in the treatment of various solid tumors, including colorectal, breast, head and neck, and gastrointestinal cancers. Mechanism of Action of 5-Fluorouracil centers on its ability to inhibit DNA and RNA synthesis, leading to impaired cell proliferation. As a pyrimidine analog, 5-FU interferes with rapidly dividing cancer … Read more