We have provided 50 MCQs on Non Aqueous titration Unit-2, 1st semester, Pharmaceutical Analysis, B. Pharm.
We have covered following topics.
Solvents, acidimetry and alkalimetry titration and estimation of Sodium benzoate and Ephedrine HCl.
Table of Contents
MCQs on Non Aqueous Titration
- In non-aqueous titrations, which type of solvents are commonly used as the titration medium?
- A) Aqueous solvents
- B) Non-polar solvents
- C) Organic solvents
- D) Gaseous solvents
Correct Answer: C) Organic solvents
- What is the primary advantage of using non-aqueous solvents in titrations over aqueous solvents?
- A) Non-aqueous solvents are less expensive.
- B) Non-aqueous solvents are environmentally friendly.
- C) Non-aqueous solvents can dissolve a wider range of substances.
- D) Non-aqueous solvents have a higher heat capacity.
Correct Answer: C) Non-aqueous solvents can dissolve a wider range of substances.
- In acidimetry, what type of substances are typically titrated?
- A) Acids
- B) Bases
- C) Neutral substances
- D) Non-metallic elements
Correct Answer: A) Acids
- Which indicator is commonly used in acidimetry titrations to signal the endpoint when titrating acids with a strong base in non-aqueous solvents?
- A) Phenolphthalein
- B) Bromothymol blue
- C) Methyl orange
- D) Litmus paper
Correct Answer: A) Phenolphthalein
- In alkalimetry, what type of substances are typically titrated?
- A) Acids
- B) Bases
- C) Neutral substances
- D) Gases
Correct Answer: B) Bases
- Which indicator is commonly used in alkalimetry titrations to signal the endpoint when titrating bases with a strong acid in non-aqueous solvents?
- A) Phenolphthalein
- B) Bromothymol blue
- C) Methyl orange
- D) Litmus paper
Correct Answer: C) Methyl orange
- How can you determine the endpoint in non-aqueous titrations when a suitable indicator is not available?
- A) By observing a color change in the solvent
- B) By measuring the electrical conductivity of the solution
- C) By titrating until a specific volume of titrant is added
- D) By using a pH meter to monitor pH changes
Correct Answer: D) By using a pH meter to monitor pH changes
- Sodium benzoate is often estimated by which type of non-aqueous titration?
- A) Acidimetry
- B) Alkalimetry
- C) Redox titration
- D) Complexometric titration
Correct Answer: A) Acidimetry
- In the estimation of Sodium benzoate by acidimetry, what is the titrant commonly used?
- A) Hydrochloric acid (HCl)
- B) Sodium hydroxide (NaOH)
- C) Sulfuric acid (H2SO4)
- D) Acetic acid (CH3COOH)
Correct Answer: A) Hydrochloric acid (HCl)
- Ephedrine HCl is often estimated by which type of non-aqueous titration?
- A) Acidimetry
- B) Alkalimetry
- C) Redox titration
- D) Complexometric titration
Correct Answer: B) Alkalimetry
- In non-aqueous titration for the estimation of Sodium benzoate, what is the indicator commonly used to signal the endpoint?
- A) Phenolphthalein
- B) Methyl orange
- C) Bromothymol blue
- D) Thymolphthalein
Correct Answer: D) Thymolphthalein
- Ephedrine HCl can be estimated by alkalimetry using a strong base. Which base is typically used as the titrant?
- A) Sodium hydroxide (NaOH)
- B) Potassium hydroxide (KOH)
- C) Ammonium hydroxide (NH4OH)
- D) Calcium hydroxide (Ca(OH)2)
Correct Answer: A) Sodium hydroxide (NaOH)
- What is the chemical formula of Ephedrine HCl?
- A) C6H12O6
- B) C8H10N
- C) C10H15NO
- D) C6H5OH
Correct Answer: C) C10H15NO
- In non-aqueous titration, what is the purpose of a back titration?
- A) To determine the initial concentration of the titrant
- B) To confirm the accuracy of the primary titration
- C) To neutralize excess titrant
- D) To accelerate the titration process
Correct Answer: B) To confirm the accuracy of the primary titration
- What technique is often used to standardize the titrant in non-aqueous titrations?
- A) Gravimetric analysis
- B) Redox titration
- C) Complexometric titration
- D) Back titration
Correct Answer: D) Back titration
- Which of the following statements is true regarding the choice of solvent in non-aqueous titrations?
- A) Polar solvents are always preferred.
- B) Non-polar solvents are always preferred.
- C) The choice of solvent depends on the nature of the analyte and titrant.
- D) Non-aqueous solvents are not suitable for titrations.
Correct Answer: C) The choice of solvent depends on the nature of the analyte and titrant.
- What is the role of Thymolphthalein in the estimation of Sodium benzoate by non-aqueous titration?
- A) It acts as a strong acid.
- B) It acts as a weak base.
- C) It serves as an indicator.
- D) It serves as a reducing agent.
Correct Answer: C) It serves as an indicator.
- In non-aqueous titrations, what is the primary factor that affects the choice of indicator?
- A) The color of the indicator
- B) The cost of the indicator
- C) The solubility of the indicator in the solvent
- D) The molecular weight of the indicator
Correct Answer: A) The color of the indicator
- Which of the following is a common source of error in non-aqueous titrations?
- A) Incorrect choice of solvent
- B) Inaccurate temperature control
- C) Choice of an unsuitable indicator
- D) Excessive use of back titration
Correct Answer: B) Inaccurate temperature control
- What is the primary advantage of non-aqueous titrations over traditional aqueous titrations?
- A) Non-aqueous titrations are faster.
- B) Non-aqueous titrations are less expensive.
- C) Non-aqueous titrations can be used for a wider range of analytes.
- D) Non-aqueous titrations are less hazardous.
Correct Answer: C) Non-aqueous titrations can be used for a wider range of analytes.
- In non-aqueous titrations, why are non-aqueous solvents such as methanol or acetic acid often preferred over water?
- A) Non-aqueous solvents are less expensive.
- B) Non-aqueous solvents have a higher heat capacity.
- C) Non-aqueous solvents can dissolve a wider range of substances.
- D) Non-aqueous solvents are environmentally friendly.
Correct Answer: C) Non-aqueous solvents can dissolve a wider range of substances.
- What is the primary difference between acidimetry and alkalimetry titrations in non-aqueous solvents?
- A) Acidimetry titrations use strong acids as titrants, while alkalimetry titrations use strong bases.
- B) Acidimetry titrations use strong bases as titrants, while alkalimetry titrations use strong acids.
- C) Acidimetry titrations determine the acidity of a sample, while alkalimetry titrations determine the alkalinity.
- D) Acidimetry titrations are always conducted in water, while alkalimetry titrations are conducted in non-aqueous solvents.
Correct Answer: A) Acidimetry titrations use strong acids as titrants, while alkalimetry titrations use strong bases.
- Which of the following statements is true about the role of Thymolphthalein in non-aqueous titrations?
- A) It serves as a reducing agent.
- B) It serves as a strong base.
- C) It acts as an indicator and changes color near the endpoint.
- D) It has no role in non-aqueous titrations.
Correct Answer: C) It acts as an indicator and changes color near the endpoint.
- In non-aqueous titrations, why is accurate temperature control important?
- A) Temperature affects the solubility of the analyte.
- B) Temperature has no impact on the titration process.
- C) Accurate temperature control prevents the need for indicators.
- D) Temperature affects the choice of solvent.
Correct Answer: A) Temperature affects the solubility of the analyte.
- What is the primary purpose of back titration in non-aqueous titrations?
- A) To speed up the titration process
- B) To confirm the accuracy of the primary titration
- C) To increase the solubility of the analyte
- D) To reduce the amount of titrant required
Correct Answer: B) To confirm the accuracy of the primary titration.
- Which of the following is NOT a common source of error in non-aqueous titrations?
- A) Incorrect choice of solvent
- B) Inaccurate temperature control
- C) Choice of a suitable indicator
- D) Inadequate mixing during titration
Correct Answer: C) Choice of a suitable indicator.
- In non-aqueous titrations, what does the choice of indicator depend on?
- A) The cost of the indicator
- B) The color of the indicator
- C) The temperature of the solvent
- D) The type of titrant used
Correct Answer: B) The color of the indicator.
- What is the primary advantage of non-aqueous titrations over traditional aqueous titrations when estimating substances with low water solubility?
- A) Non-aqueous titrations are more accurate.
- B) Non-aqueous titrations are faster.
- C) Non-aqueous titrations can dissolve a wider range of substances.
- D) Non-aqueous titrations are less hazardous.
Correct Answer: C) Non-aqueous titrations can dissolve a wider range of substances.
- Which of the following is an example of a common non-aqueous titration technique?
- A) Acid-base titration in water
- B) Complexometric titration in acetone
- C) Redox titration in ethanol
- D) Alkalimetry in sulfuric acid
Correct Answer: B) Complexometric titration in acetone.
- What is the primary objective of non-aqueous titrations?
- A) To determine the molar mass of the analyte
- B) To estimate the concentration of water in a sample
- C) To determine the concentration of a specific substance in a sample
- D) To neutralize a solution
Correct Answer: C) To determine the concentration of a specific substance in a sample.
- When estimating Ephedrine HCl through alkalimetry, what is the role of the strong base titrant?
- A) To neutralize Ephedrine HCl
- B) To oxidize Ephedrine HCl
- C) To reduce Ephedrine HCl
- D) To dissolve Ephedrine HCl
Correct Answer: A) To neutralize Ephedrine HCl
- Why is it essential to perform non-aqueous titrations in a controlled environment with minimal exposure to moisture or humidity?
- A) Moisture can affect the choice of indicator.
- B) Non-aqueous solvents are sensitive to humidity.
- C) Humidity can react with the titrant.
- D) Moisture can affect the accuracy of the titration.
Correct Answer: B) Non-aqueous solvents are sensitive to humidity.
- In non-aqueous titrations, what is the primary function of a solvent like acetic acid?
- A) To serve as an indicator
- B) To increase the solubility of the analyte
- C) To accelerate the titration process
- D) To neutralize the analyte
Correct Answer: B) To increase the solubility of the analyte
- What is the primary disadvantage of using non-aqueous solvents in titrations?
- A) Limited applicability for various analytes
- B) High cost of non-aqueous solvents
- C) Increased environmental impact
- D) Requirement for specialized equipment
Correct Answer: C) Increased environmental impact
- Which type of analyte is particularly well-suited for non-aqueous titrations due to its low solubility in water?
- A) Highly polar substances
- B) Non-polar substances
- C) Substances with low water solubility
- D) Gases
Correct Answer: C) Substances with low water solubility
- In non-aqueous titrations, why is it crucial to keep the temperature of the solvent consistent throughout the titration?
- A) Temperature affects the choice of titrant.
- B) Temperature can alter the solubility of the titrant.
- C) Temperature affects the color of the indicator.
- D) Temperature can change the endpoint of the titration.
Correct Answer: B) Temperature can alter the solubility of the titrant.
- What is the primary role of a back titration in non-aqueous titrations?
- A) To confirm the accuracy of the primary titration
- B) To speed up the titration process
- C) To neutralize the analyte
- D) To dissolve the analyte
Correct Answer: A) To confirm the accuracy of the primary titration
- Which indicator is typically used when estimating Ephedrine HCl through alkalimetry?
- A) Phenolphthalein
- B) Bromothymol blue
- C) Methyl orange
- D) Thymolphthalein
Correct Answer: A) Phenolphthalein
- In non-aqueous titrations, why is the choice of indicator critical for the accuracy of the titration?
- A) Indicators determine the choice of titrant.
- B) Indicators can introduce errors in pH measurements.
- C) Indicators must be dissolved in water for accuracy.
- D) Indicators signal the endpoint of the titration.
Correct Answer: D) Indicators signal the endpoint of the titration.
- What is the primary application of non-aqueous titrations in pharmaceutical analysis?
- A) Determining the water content in drugs
- B) Measuring the concentration of non-polar compounds
- C) Estimating the pH of pharmaceutical solutions
- D) Analyzing the solubility of pharmaceuticals in water
Correct Answer: A) Determining the water content in drugs
- In non-aqueous titration, when estimating the water content in pharmaceuticals, which solvent is typically used to dissolve the sample?
- A) Water
- B) Ethanol
- C) Acetic acid
- D) Hexane
Correct Answer: B) Ethanol
- Why is it important to use a solvent like ethanol in the estimation of water content in pharmaceuticals by non-aqueous titration?
- A) Ethanol is less expensive than water.
- B) Ethanol prevents the reaction between the sample and the titrant.
- C) Ethanol has a lower boiling point, facilitating titration.
- D) Ethanol can effectively dissolve water-soluble components.
Correct Answer: D) Ethanol can effectively dissolve water-soluble components.
- In non-aqueous titration, what is the primary function of the titrant?
- A) To dissolve the analyte
- B) To react with the indicator
- C) To neutralize the analyte
- D) To change the color of the solvent
Correct Answer: C) To neutralize the analyte
- In non-aqueous titrations, why is the endpoint often determined by monitoring a change in color?
- A) Non-aqueous solvents are typically colorless.
- B) Color changes are less noticeable in non-aqueous solvents.
- C) The titrant itself has a distinct color.
- D) Non-aqueous titrations do not use indicators.
Correct Answer: C) The titrant itself has a distinct color.
- Which type of pharmaceuticals is particularly suited for non-aqueous titration to determine water content?
- A) Solids
- B) Liquids
- C) Gases
- D) Lipophilic drugs
Correct Answer: D) Lipophilic drugs
- In non-aqueous titration, what is the term for the volume of titrant required to reach the endpoint?
- A) Blank volume
- B) Titer
- C) Equivalence volume
- D) Indicator volume
Correct Answer: C) Equivalence volume
- What is the primary purpose of conducting a blank titration in non-aqueous titration?
- A) To determine the concentration of the titrant
- B) To establish a baseline for color change
- C) To confirm the accuracy of the titration apparatus
- D) To calculate the molar mass of the analyte
Correct Answer: B) To establish a baseline for color change
- Which of the following is an example of a pharmaceutical where water content is critical and may be determined by non-aqueous titration?
- A) Metal alloys
- B) Glassware
- C) Liquid vitamins
- D) Capsules
Correct Answer: D) Capsules
- In non-aqueous titration, if the titration curve does not exhibit a clear endpoint, what step can be taken to improve accuracy?
- A) Increase the temperature
- B) Change the titrant
- C) Use a more sensitive indicator
- D) Repeat the titration with a larger sample
Correct Answer: C) Use a more sensitive indicator
- What is the primary advantage of using non-aqueous titration for the estimation of water content in pharmaceuticals?
- A) It is faster than other methods.
- B) It provides more accurate results.
- C) It does not require solvents.
- D) It is suitable for all types of pharmaceuticals.
Correct Answer: B) It provides more accurate results.
More MCQs
Semester- 1
Human Anatomy & PhysiolPharmaceutical analysisogy
- Unit-1
- Unit-2
- Unit-3
- Unit-4
- Unit-5
Pharmaceutical analysis
- Unit-1
- Unit-2
- Unit-3
- Unit-4
- Unit-5
PHARMACEUTICS- I
- Unit-1