CLASSIFICATION OF GANGLIONIC BLOCKING AGENTS

Ganglionic blocking agents

Ganglionic blocking agents, also known as ganglionic blockers, are a class of drugs that act on the autonomic nervous system by blocking the transmission of nerve impulses at the ganglia, which are clusters of nerve cell bodies outside the central nervous system. Ganglionic blockers are not commonly used today, but they were once used to treat conditions such as hypertension, angina, and some types of autonomic dysfunction.

Classification

GANGLIONIC BLOCKING AGENTS

1. Competitive blockers
   • Quaternary ammonium comps.– Hexamethonium, Pentolinium
   • Amines– Mecamylamine, Pempidine
   • Monosulfonium comp.- Trimethaphan-camforsulfonate
2. Persistent depolarizing blockers– Nicotine (large dose), Anticholinesterases (large dose)

Related links

• Classification of Ganglionic Stimulants
• Classification Of Anticholinargic Drugs
• Classification of Cholinergic drugs

Reference

• CLASSIFICATION OF DRUGS- KD Tripathi
• National Library of Medicine- Nicotinic Ganglionic Blocker (Suraj Kaushal; Prasanna Tadi).