CLASSIFICATION OF GANGLIONIC BLOCKING AGENTS

Ganglionic blocking agents

A family of medications known as ganglionic blocking agents, also referred to as ganglionic blockers, affects the autonomic nervous system by preventing the transmission of nerve impulses at ganglia, which are collections of nerve cell bodies outside the central nervous system. Ganglionic blockers were once used to address conditions like hypertension, angina, and some forms of autonomic dysfunction, but they are no longer frequently prescribed.

Classification

ganglionic blocking agents classification - KD Tripathi
classification of ganglionic blocking agents

GANGLIONIC BLOCKING AGENTS

  1. Competitive blockers
    • Quaternary ammonium comps.– Hexamethonium, Pentolinium
    • Amines– Mecamylamine, Pempidine
    • Monosulfonium comp.- Trimethaphan-camforsulfonate
  2. Persistent depolarizing blockers– Nicotine (large dose), Anticholinesterases (large dose)

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