Ganglionic blocking agents
A family of medications known as ganglionic blocking agents, also referred to as ganglionic blockers, affects the autonomic nervous system by preventing the transmission of nerve impulses at ganglia, which are collections of nerve cell bodies outside the central nervous system. Ganglionic blockers were once used to address conditions like hypertension, angina, and some forms of autonomic dysfunction, but they are no longer frequently prescribed.
Classification

GANGLIONIC BLOCKING AGENTS
- Competitive blockers
- Quaternary ammonium comps.– Hexamethonium, Pentolinium
- Amines– Mecamylamine, Pempidine
- Monosulfonium comp.- Trimethaphan-camforsulfonate
- Persistent depolarizing blockers– Nicotine (large dose), Anticholinesterases (large dose)
Related links
- Classification of Ganglionic Stimulants
- Classification Of Anticholinargic Drugs
- Classification of Cholinergic drugs
Reference
- CLASSIFICATION OF DRUGS- KD Tripathi
- National Library of Medicine- Nicotinic Ganglionic Blocker (Suraj Kaushal; Prasanna Tadi).
Authors
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Pharmacy Freak Editorial Team: AuthorPharmacy Freak Editorial Team is the official editorial voice of PharmacyFreak.com, dedicated to creating high-quality educational resources for healthcare learners. Our team publishes and reviews exam preparation content across pharmacy, nursing, coding, social work, and allied health topics, with a focus on practice questions, study guides, concept-based learning, and practical academic support. We combine subject research, structured editorial review, and clear presentation to make difficult topics more accessible, accurate, and useful for learners preparing for exams and professional growth.
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G S Sachin: ReviewerG S Sachin is a Registered Pharmacist under the Pharmacy Act, 1948, and the founder of PharmacyFreak.com. He holds a Bachelor of Pharmacy degree from Rungta College of Pharmaceutical Science and Research and creates clear, accurate educational content on pharmacology, drug mechanisms of action, pharmacist learning, and GPAT exam preparation.
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