Mechanism of Action of Mesalamine
Introduction Mesalamine (5-aminosalicylic acid, 5-ASA) is an anti-inflammatory drug primarily used in the treatment of inflammatory bowel diseases such as ulcerative colitis and, in some cases, Crohn disease. It acts locally on the intestinal mucosa to reduce inflammation. Unlike systemic anti-inflammatory drugs, mesalamine exerts its effect mainly within the gastrointestinal tract with minimal systemic absorption. … Read more