carbonic anhydrase inhibitors

Introduction Carbonic anhydrase inhibitors (CAIs) are a class of diuretics and antiglaucoma drugs represented primarily by acetazolamide, dorzolamide, and brinzolamide. They reduce bicarbonate reabsorption in the kidney, decrease aqueous humor formation in the eye, and modulate cerebrospinal fluid (CSF) production. The Mechanism of Action of Carbonic Anhydrase Inhibitors centers on blocking the enzyme carbonic anhydrase … Read more