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Mechanism of Action of Finasteride

mechanism of action of finasteride

Introduction Finasteride is a synthetic 4-azasteroid that functions as a competitive and specific inhibitor of type II 5-alpha-reductase, the enzyme responsible for the conversion of testosterone to dihydrotestosterone (DHT). DHT is a potent androgen involved in the pathogenesis of benign prostatic hyperplasia (BPH) and androgenetic alopecia. By reducing DHT levels, finasteride alleviates symptoms associated with … Read more

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