Acids, Bases and Buffers MCQs - Pharmacy Freak

# Acids, Bases and Buffers MCQs

We have provided 30 MCQs on Acids, Bases and Buffers, Unit-2, 1st semester, PHARMACEUTICAL INORGANIC CHEMISTRY, B. Pharm.

We have covered following topics.

Acids, Bases and Buffers: Buffer equations and buffer capacity in general, buffers in pharmaceutical systems, preparation, stability, buffered isotonic solutions, measurements of tonicity, calculations and methods of adjusting isotonicity.

## MCQ on Acids, Bases and Buffers MCQs

Question 1: Which of the following is a buffer solution?

Options:

• (A) A solution containing a weak acid and its strong conjugate base
• (B) A solution containing a strong acid and its weak conjugate base
• (C) A solution containing a weak base and its strong conjugate acid
• (D) A solution containing a strong base and its weak conjugate acid

Question 2: Which of the following is the Henderson-Hasselbalch equation?

Options:

• (A) pH = pKa + log10([A-]/[HA])
• (B) pH = pKa – log10([A-]/[HA])
• (C) pH = pKa + log10([HA]/[A-])
• (D) pH = pKa – log10([HA]/[A-])

Question 3: Which of the following is a factor that affects the buffer capacity of a solution?

Options:

• (A) The concentration of the weak acid and its conjugate base
• (B) The pH of the solution
• (C) The pKa of the weak acid
• (D) All of the above

Question 4: Which of the following is a common use of buffers in pharmaceutical systems?

Options:

• (A) To maintain a constant pH
• (B) To improve the solubility of drugs
• (C) To increase the stability of drugs
• (D) All of the above

Question 5: Which of the following is a common method for preparing buffered solutions?

Options:

• (A) Mixing a weak acid with its strong conjugate base
• (B) Mixing a strong acid with its weak conjugate base
• (C) Mixing a weak base with its strong conjugate acid
• (D) Mixing a strong base with its weak conjugate acid

Question 6: Which of the following factors can affect the stability of buffered solutions?

Options:

• (A) Temperature
• (B) Light
• (C) pH
• (D) All of the above

Question 7: What is the difference between an isotonic solution and a hypertonic solution?

Options:

• (A) An isotonic solution has the same osmotic pressure as blood, while a hypertonic solution has a higher osmotic pressure than blood.
• (B) An isotonic solution has a lower osmotic pressure than blood, while a hypertonic solution has the same osmotic pressure as blood.
• (C) An isotonic solution has a higher osmotic pressure than blood, while a hypertonic solution has a lower osmotic pressure than blood.
• (D) An isotonic solution has the same osmotic pressure as a different solution, while a hypertonic solution has a higher osmotic pressure than a different solution.

Question 8: Which of the following is a common method for adjusting the tonicity of a solution?

Options:

• (D) All of the above

Question 9: Which of the following is a common use of isotonic solutions in medicine?

Options:

• (A) To administer drugs intravenously
• (B) To clean wounds
• (C) To rehydrate patients
• (D) All of the above

Question 10: Which of the following is a method for measuring the tonicity of a solution?

Options:

• (A) Osmolality
• (B) Osmolarity
• (C) Vapor pressure osmometry
• (D) All of the above

Question 11: Which of the following is a true statement about buffer capacity?

Options:

• (A) Buffer capacity is a measure of how well a buffer solution can resist changes in pH.
• (B) Buffer capacity is directly proportional to the concentration of the weak acid and its conjugate base.
• (C) Buffer capacity is inversely proportional to the pKa of the weak acid.
• (D) All of the above are true statements about buffer capacity.

Question 12: Which of the following is a true statement about buffers in pharmaceutical systems?

Options:

• (A) Buffers are used to maintain a constant pH, improve the solubility of drugs, and increase the stability of drugs.
• (B) Buffers are typically prepared by mixing a weak acid with its strong conjugate base.
• (C) The stability of buffered solutions can be affected by temperature, light, and pH.
• (D) All of the above are true statements about buffers in pharmaceutical systems.

Question 13: Which of the following is a true statement about isotonic solutions?

Options:

• (A) Isotonic solutions have the same osmotic pressure as blood.
• (B) Isotonic solutions are commonly used to administer drugs intravenously, clean wounds, and rehydrate patients.
• (C) The tonicity of a solution can be measured using osmolality, osmolarity, or vapor pressure osmometry.
• (D) All of the above are true statements about isotonic solutions.

Question 14: Which of the following is a buffered isotonic solution?

Options:

• (A) Normal saline
• (B) Lactated Ringer’s solution
• (C) Dextrose 5% in water
• (D) All of the above

Question 15: Which of the following is a method for preparing a buffered isotonic solution?

Options:

• (A) Mixing sodium chloride with sodium bicarbonate
• (B) Mixing sodium lactate with sodium chloride
• (C) Mixing dextrose with sodium chloride
• (D) All of the above

Question 16: Which of the following is a factor that can affect the stability of a buffered isotonic solution?

Options:

• (A) Temperature
• (B) Light
• (C) pH
• (D) All of the above

Question 17: Which of the following is a common use of buffered isotonic solutions in medicine?

Options:

• (A) To administer drugs intravenously
• (B) To clean wounds
• (C) To rehydrate patients
• (D) All of the above

Question 18: Which of the following is a true statement about buffered isotonic solutions?

Options:

• (A) Buffered isotonic solutions are used to maintain a constant pH.
• (B) Buffered isotonic solutions are commonly used to administer drugs intravenously, clean wounds, and rehydrate patients.
• (C) The stability of buffered solutions can be affected by temperature, light, and pH.
• (D) All of the above are true statements about buffered isotonic solutions.

Question 19: Which of the following is an example of a buffered isotonic solution that is used to administer drugs intravenously?

Options:

• (A) Normal saline
• (B) Lactated Ringer’s solution
• (C) Dextrose 5% in water
• (D) All of the above

Question 20: Which of the following is an example of a buffered isotonic solution that is used to clean wounds?

Options:

• (A) Normal saline
• (B) Lactated Ringer’s solution
• (C) Dextrose 5% in water
• (D) All of the above

Question 21: Which of the following is an example of a buffered isotonic solution that is used to rehydrate patients?

Options:

• (A) Normal saline
• (B) Lactated Ringer’s solution
• (C) Dextrose 5% in water
• (D) All of the above

Question 22: Which of the following is a true statement about the Henderson-Hasselbalch equation?

Options:

• (A) The Henderson-Hasselbalch equation can be used to calculate the pH of a buffer solution given the concentrations of the weak acid and its conjugate base.
• (B) The Henderson-Hasselbalch equation can be used to calculate the buffer capacity of a solution given the concentrations of the weak acid and its conjugate base.
• (C) The Henderson-Hasselbalch equation can be used to calculate the pKa of a weak acid given the pH of a buffer solution containing the weak acid and its conjugate base.
• (D) All of the above are true statements about the Henderson-Hasselbalch equation.

Question 23: Which of the following is a common method for preparing a buffered isotonic solution containing a drug?

Options:

• (A) Mixing the drug with sodium chloride and sodium bicarbonate.
• (B) Mixing the drug with sodium lactate and sodium chloride.
• (C) Mixing the drug with dextrose and sodium chloride.
• (D) All of the above.

Question 24: Which of the following is a factor that can affect the solubility of a drug in a buffered isotonic solution?

Options:

• (A) The pH of the solution
• (B) The temperature of the solution
• (C) The presence of salts in the solution
• (D) All of the above

Question 25: Which of the following is a true statement about the stability of buffered isotonic solutions?

Options:

• (A) Buffered isotonic solutions are generally more stable than non-buffered solutions.
• (B) The stability of buffered isotonic solutions can be affected by temperature, light, and pH.
• (C) Buffered isotonic solutions should be stored in a cool, dark place to maximize their stability.
• (D) All of the above are true statements about the stability of buffered isotonic solutions.

Question 26: Which of the following is a true statement about the use of buffered isotonic solutions in medicine?

Options:

• (A) Buffered isotonic solutions are commonly used to administer drugs intravenously, clean wounds, and rehydrate patients.
• (B) Buffered isotonic solutions can also be used to irrigate wounds and flush out toxins from the body.
• (C) Buffered isotonic solutions are generally safe and well-tolerated by patients.
• (D) All of the above are true statements about the use of buffered isotonic solutions in medicine.

Question 27: Which of the following is an example of a buffered isotonic solution that is used to irrigate wounds?

Options:

• (A) Normal saline
• (B) Lactated Ringer’s solution
• (C) Dextrose 5% in water
• (D) All of the above

Question 28: Which of the following is an example of a buffered isotonic solution that is used to flush out toxins from the body?

Options:

• (A) Normal saline
• (B) Lactated Ringer’s solution
• (C) Dextrose 5% in water
• (D) All of the above

Question 29: Which of the following is a true statement about the safety and tolerability of buffered isotonic solutions?

Options:

• (A) Buffered isotonic solutions are generally safe and well-tolerated by patients.
• (B) However, buffered isotonic solutions can cause side effects such as nausea, vomiting, and diarrhea.
• (C) In rare cases, buffered isotonic solutions can cause serious side effects such as heart failure and seizures.
• (D) All of the above are true statements about the safety and tolerability of buffered isotonic solutions.