MCQ / multiple choice questions of pharmacognosy and phytochemistry with answers. Check our site for GPAT and B.pharm preparations.
1. The change in the specific rotation due to interconversion of a form into B form or vice versa is known as
- (a) Mutarotation
- (b) Epimerisation
- (c) Isomerisation
- (d) Cyclization
Answer – (a) Mutarotation
2. Mutarotation takes place in
- (a) acidic solvent
- (b) basic solvent
- (c) amphoteric solvent
- (d) aprotic solvent
Answer – (c) amphoteric solvent
3. There are two isomers present in glucose solutions. Identify the major isomer
- (a) a-D-glucose
- (b) B-D-glucose
- (c) a-D-glucose or B-D-glucose depending on pH
- (d) None of the above
Answer – (c) a-D-glucose or B-D-glucose depending on pH
4. The a and b anomer can be differentiated by
- (a) IR spectrum
- (b) NMR spectrum
- (c) UV spectrum
- (d) IR and NMR spectrum
Answer – (d) IR and NMR spectrum
5. In ß-D glucose, the-OH groups at
- (a) C₁, C₂, C3, C4, and C5 positions are equatorial
- (b) C1 is axial but on C₂, C3, C4, and C5, positions are equatorial
- (c) C₁, C₂, C3, C4, and C5, are axial
- (d) C₂, C₁, C, and C positions are axial but C1 is equatorial
Answer – (a) C₁, C₂, C3, C4, and C5 positions are equatorial
6. Commercially, glucose is obtained from
- (a) alkaline hydrolysis of starch
- (b) acidic hydrolysis of starch
- (c) acidic hydrolysis of sucrose
- (d) acidic hydrolysis of malt sugar
Answer – (b) acidic hydrolysis of starch
7. The glucose is not reactive with :
- (a) Tollen’s reagent
- (b) sodium bisulfite solution
- (c) acetic anhydride
- (d) hydroxylamine
Answer – b) sodium bisulfite solution
8. The no. of optical isomers in fructose is
- (a) 16
- (b) 4
- (c) 8
- (d) 10
Answer – (c) 8
9. Fructose is obtained from
- (a) Sucrose
- (b) Cellulose
- (c) Inulin
- (d) Any of the above
Answer – (c) Inulin
10. Galactose sugar is present in
- (a) Sucrose
- (b) Maltose
- (c) Lactose
- (d) Gentiobiose
Answer – (c) Lactose
11. Amygdalin on hydrolysis with dilute hydrochloric acid
- (a) C6H5CHO, HCN and 2C6H12O6
- (b) C6H5CH(CN)O6511O6
- (c) C6H5CHO and 2C6H₁₂O6
- (d) C6H5CHO and HCN
Answer – (a) C6H5CHO, HCN and 2C6H12O6
12. Sucrose is not reactive with
- (a) acetic anhydride
- (b) hydrochloric acid
- (c) periodic acid
- (d) Fehling solution
Answer – (d) Fehling solution
13. Dextrorotatory sucrose gives the levorotatory product on hydrolysis. Identify the product
- (a) B-D (+) fructofuranose
- (b) B-D (-) fructopyranose
- (c) B-D (-) glucopyranose
- (d) B-D (-) galactopyranose
Answer – (b) B-D (-) fructopyranose
14. Identify the sweetest sugar among these
- (a) Sucrose
- (b) Invert sugar
- (c) D-fructose
- (d) D-glucose
Answer – (c) D-fructose
15. 4-(a-D-glucopyranosyl) – B-D-glucopyranose is name for
- (a) Lactose
- (b) Maltose
- (c) Sucrose
- (d) Cellobiose
Answer – (b) Maltose
16. Amylopectin, soluble in water reacts with iodine to give
- (a) blue color
- (b) red violet color
- (c) colorless solution
- (d) any color depending on the source of amylopectin
Answer – (b) red violet color
17. On complete hydrolysis, inulin gives
- (a) D-fructose
- (b) D-glucose
- (c) L-fructose
- (d) D-fructose cd D-glucose (small amount)
Answer – (d) D-fructose cd D-glucose (small amount)
18. Which one is a sulfur-containing amino acid?
- (a) Methionine
- (b) Leucine
- (c) Valine
- (d) Lysine
Answer – (a) Methionine
19. Chinese restaurant syndrome occurs due to an excess of specific amino acids in the body. Identify the amino acid
- (a) Aspartic acid
- (b) Glutamic acid
- (c) Thyroxine
- (d) Tryptophan
Answer – (b) Glutamic acid
20. IR spectrum of amino acid does not show the characteristic band for the presence of the COOH group. It is due to
- (a) presence of zwitterion
- (b) presence of lactone
- (c) presence of carboxylic acid in complex form
- (d) decomposition reaction
Answer – (a) presence of zwitterion
21. a-Amino acid or heating form
- (a) y-lactam
- (b) diketopiperazine
- (c) S-lactam
- (d) Syndrome
Answer – (b) diketopiperazine
22. Syndromes is a product of amino acid. These are
- (a) cyclic diamide, formed on heating the amino acid
- (b) formed by dehydration of N-nitroso derivative of N-aryl amino acid
- (c) a-acidamidoketone, formed by heating amino acid with acetic anhydride in pyridine solution
- (d) the product of amino acid with ninhydrin
Answer – (b) formed by dehydration of N-nitroso derivative of N-aryl amino acid
23. Ninhydrin is
- (a) Indane – 1, 2, 4 trione
- (b) Indane – 1, 3, 4 – trione
- (c) Indole – 1, 2, 3 – trione
- (d) Indane 1, 2, 3 trione
Answer – (d) Indane 1, 2, 3 trione
24. Chemically Sanger’s reagent is
- (a) 1-fluoro 2, 6- dinitro benzene
- (b) 1-fluoro 2, 4 – dinitro benzene
- (c) 2-fluoro 1, 4- dinitro benzene
- (d) 1-fluoro 3, 5- dinitro benzene
Answer – (a) 1-fluoro 2, 6- dinitro benzene
25. The 1-dimethyl amino naphthalene- 5- sulphonyl chloride is known as
- (a) Dansyl chloride.
- (b) Edman reagent
- (c) Schack reagent
- (d) None of the above
Answer – (a) Dansyl chloride.
26. The protein on reaction with alkaline copper sulfate solution develops reddish violet coloration. It is an indication of
- (a) presence of -NH-CO-NH-group
- (b) presence of-CONH-CH-CO-NH-group – R
- (c) -CONH-CO-NH-group
- (d) —NH–CH CONH
Answer – (b) presence of-CONH-CH-CO-NH-group – R
27. The presence of aromatic amino acids can be identified by
- (a) Ninhydrin reaction
- (b) Biuret test
- (c) Xanthoproteic test
- (d) Million test
Answer – (c) Xanthoproteic test
28. Hemoglobin contains
- (a) Fibrous protein
- (b) Globular protein
- (c) Derived protein
- (d) None of the above
Answer – (b) Globular protein
29. The tertiary structure of protein indicate
- (a) arrangement of individual peptide chains in a protein molecule
- (b) the number of the peptide chain and their arrangement in a protein molecule
- (c) the forces with which the peptide chains are held together
- (d) All of the above
Answer – (a) arrangement of individual peptide chains in a protein molecule
30. The polypeptide chains in insulin have more are held together by
- (a) oxy linkage
- (b) disulfide linkage
- (c) carbon linkage
- (d) carboxy linkage
Answer – (b) disulfide linkage
31. Potassium mercuric iodide is a constituent of
- (a) Dragendoff’s reagent
- (b) Mayer’s reagent
- (c) Wagner reagent
- (d) Scheibler’s reagent
Answer – (b) Mayer’s reagent
32. Which one of these alkaloids is optically inactive?
- (a) Nicotine
- (b) Conine
- (c) Papaverine
- (d) Moscapine
Answer – (c) Papaverine
33. Which one of these alkaloids is steam volatile and water-soluble?
- (a) Nicotine
- (b) Ajmaline
- (c) Conine
- (d) Hygrine
Answer – (a) Nicotine
34. The number of alkoxyl groups is determined by the method, designated as
- (a) Herzig-Meyer
- (b) Zeisel
- (c) Kyeldahl
- (d) Hofmann methylation
Answer – (b) Zeisel
35. Piperidine on Hofmann’s exhaustive methylation yield.
- (a) Piperylene
- (b) Piperine
- (c) buta-diene
- (d) pent-1 ene
Answer – (a) Piperylene
36. Ephedrine hydrochloride on heating gives propiophenone, phenylacetone, and methylamine. It is due to the presence of characteristic moiety. Identify it
- (a) C6H5CHOH—CH—NHR
- (b) C6H5CH2OH—CH–NHR
- (c) C6H5CHOH-CH-NH2
- (d) CH₂CHOH₂-CH-OH
Answer – (a) C6H5CHOH—CH—NHR
37. The appropriate starting material for the synthesis of nicotine is
- (a) Nicotinic acid and N-methyl pyrrolidine
- (b) Ethyl nicotinate and N-methyl pyrrolidone
- (c) Ethyl nicotinate and N-methyl pyrrole 2, 4-dione
- (d) Any of the above
Answer –
38. Atropine is
- (a) levoform
- (b) dextroform
- (c) optically inactive
- (d) mesoform
- (e) recemicoform
Answer – (a) levoform
39. The chemical structure for tropic acid is
- (a) C6H5-CH(OH) COOH
- (b) C6H5CHCOOH
- (c) C6H5CCOOH
- (d) C6H5CCOOH
Answer – (a) C6H5-CH(OH) COOH
40. Tropine acid on oxidation with chromic oxide yield
- (a) Piperylene carboxylic acid
- (b) Pimelic acid
- (c) Tropinic acid
- (d) Atropinic acid
Answer – (c) Tropinic acid
41. Tropinone on reaction with benzaldehyde gives dibenzylidise derivative. It is characteristic of the presence of
- (a) –COCH2 group
- (b) -CH₂-CO-CH₂ group
- (c) -CO-CH₂-CH₂ group
- (d) -CH₂-CH₂ group
Answer – (b) -CH₂-CO-CH₂ group
42. The appropriate starting materials for the synthesis of tropinone according to the Robinson method are
- (a) Succinal dehyde, methylamine, and acetone dicarboxylic acid
- (b) Succinaldehyde, methylamine, and acetone
- (c) Succinal dehyde, ammonia, and acetone
- (d) Succinal dehyde, methylamine, and acetylacetone
Answer – (b) Succinaldehyde, methylamine, and acetone
43. Meroquinine on oxidation with acidic permanganate gives formic acid and dicarboxylic cincholoiponic acid. This reaction concludes
- (a) Meroquinine contains vinyl group
- (b) Meroquinine contain -CH₂COOH-moiety
- (c) Meroquinine contain-NHCH₂-moiety
- (d) None of these
Answer – (b) Meroquinine contain -CH₂COOH-moiety
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