The pharmacognosy and phytochemistry MCQs with answers. Check it out for B.Pharm and GPAT.
1. N-methyl morphinan differs from morphine in one aspect. Identify it
- (a) Ether bridge between C-4 and C-5 is absent
- (b) Hydroxy groups are absent
- (c) N-methyl group is absent
- (d) None of the above
Answer-(a) Ether bridge between C-4 and C-5 is absent
2. The benzomorphan is a modified structure of morphine. Identify the modification done to make this structure
- (a) Ether linkage is removed
- (b) Alicyclic ring is replaced by one or two methyl group
- (c) N-CH₂ group is not present
- (d) Phenolic hydroxy group is esterified
Answer- (b) Alicyclic ring is replaced by one or two methyl group
3. Apomorphine is synthesized from
- (a) orphine by heating with strong hydrochloric acid at 140°C under pressure
- (b) morphine by heating with alcoholic potassium hydroxide solution
- (c) codeine by heating with did Na OH solution
- (d) morphine by oxidation with chromic oxide chemically,
Answer-(a) orphine by heating with strong hydrochloric acid at 140°C under pressure
4.Chemically, salol is a
- (a) Methyl salicylate
- (b) Phenyl salicylate
- (C) salicylamide
- (d) Saticylsaticylic acid
Answer- (b) Phenyl salicylate
5. In 5a-steroid, the and B rings are
- (a) Trans
- (b) Cis
- (c) Cis or trans
- (d) None of the above
Answer-(a) Trans
6. The antiarrhythmic drug quinidine is
- (a) (+) stereoisomer of quinine
- (b) (-) stereoisomer of quinine
- (c) Racemic mixture of quinine
- (d) None of the above
Answer- (a) (+) stereoisomer of quinine
7. Beta carboline ring system is present in
- (a) Emetine alkaloid
- (b) Cortisone acetate
- (c) Deserpidine
- (d) Atropine
Answer- (c) Deserpidine
8. Choose the synthetic adrenocortical steroid which does not occur in nature
- (a) 113, 17a, 21 – Trihydroxy – 1,4-preg – 4-ene – 3, 20 – dione
- (b) 17a, 21-Dihydroxy preg-4-ene- 3, 11, 20- trione
- (c) 113, 17a, 21 – Trihydroxy pregna 4-ene – 3, 20-dione
- (d) 3-oxo-17ß hydroxy and rost 4 – ene
Answer- (a) 113, 17a, 21 – Trihydroxy – 1,4-preg – 4-ene – 3, 20 – dione
9. Sesquiterpene has the molecular formulae. Identify it
- (a) C5H5
- (b) C15H24
- (c) C10H16
- (d) C30H18
Answer- (b) C15H24
10. The main constituent of the Tilden reagent is
- (a) Nitrosyl chloride
- (b) Nitrosyl bromide
- (c) Iodine
- (d) Silver bromide
Answer- (a) Nitrosyl chloride
11. Chemically, isoprene is
- (a) 1,3-butadiene
- (b) 2-methyl but – 3 – ene
- (c) 2-methyl 1, 3 – butadiene
- (d) 1-methyl 1, 3 – butadiene
Answer- (c) 2-methyl 1, 3 – butadiene
12. Which one is not true regarding citral?
- (a) Citral reduces the Fehling solution
- (b) Citral forms crystalline bisulfite product
- (c) Citral on reduction forms geraniol.
- (d) Citral on bromination forms dibromide
Answer- (d) Citral on bromination forms dibromide
13. Acetone, levulinic acid, and oxalic acid are formed from citral by treatment with
- (a) KMnO, and chromic acid
- (b) KMnO4
- (c) Pot. ferricyanide
- (d) P₂05
Answer- (a) KMnO, and chromic acid
14. Neral is a
- (a) Trans – citral
- (b) Cis-citral
- (c) Citral – b
- (d) Any of the above
Answer- (b) Cis-citral
15. Dipentene is
- (a) Racemic limonene
- (b) Levo limonene
- (c) Dextra limonene
- (d) Recemic pinene
Answer- (a) Racemic limonene
16. a-Terpineol is dehydration gives
- (a) Menthol
- (b) Limonene
- (c) a-Terpene
- (d) Menthone
Answer- (b) Limonene
17. Limonene on treatment with nitrosyl chloride gives adduct.
Identify the color of the adduct.
- (a) Blue
- (b) Colourless
- (c) Green
- (d) White
Answer- (b) Colourless
18. Dibromomenthone on heating with quinoline gives
- (a) Menthol
- (b) Thymol
- (c) Neo-menthol
- (d) Iso-menthol
Answer- (b) Thymol
19. Menthone on oxidation with KMnO4 gives a keto acid which on further oxidation form
- (a) Adipic acid
- (b) B-methyl adipic acid
- (c) Glutaric acid
- (d) B-methyl glutaric acid
Answer- (b) B-methyl adipic acid
20. Adipic acid on heating form
- (a) Anhydride
- (b) Cyclopentanones
- (c) Cyclohexanones
- (d) Saturated aliphatic hydrocarbon
Answer- (b) Cyclopentanones
21. Caffeine on oxidation with potassium chlorate forms
- (a) 1,3-dimethyl alloxan and monomethyl urea
- (b) 1-methyl alloxan and monomethyl urea
- (c) 3,7-dimethyl alloxan and monomethyl urea
- (d) None of the above
Answer-
22. According to Fisher’s method, caffeine is synthesized from
- (a) Cyano ethyl acetals
- (b) 2, 6, 8-trichloropurine
- (c) monomethyl ura
- (d) 1,3-dimethyl alloxan
Answer- (a) Cyano ethyl acetals
23. Acropine on hydrolysis with barium hydroxide gives
- (a) Tropanol and Tropic acid
- (b) Scopine and Tropic acid
- (c) Ecgonine and Benzoic acid
- (d) Benzyl ecgonine and methanol
Answer- (b) Scopine and Tropic acid
24. Thiamine on treatment with sodium sulfite solution and sulfur dioxide yields
- (a) Pyrimidine and a thiazole derivative
- (b) Pyridine and thiazole derivative
- (c) 2,3,4-Trihydro pyridine and thiophene derivative
- (d) Pyrimidine and thiphene derivatives
Answer- (a) Pyrimidine and a thiazole derivative
25. Papaverine is
- (a) 6,7-dimethoxy-1-(3, 4′- dimethoxy benzyl) isoquinoline
- (b) 6,7-dimethoxy-1-(3, 4′-dimethoxy benzyl) isoquinoline
- (c) 6,7-dimethoxy-1-(3, 4′-dimethoxy benzyl) quinoline
- (d) 6,7-dimethoxy-1-(3,’ 4′-dimethoxy benzyl) isoquinoline
Answer- (d) 6,7-dimethoxy-1-(3,’ 4′-dimethoxy benzyl) isoquinoline
26. In the steroid nucleus, there are
- (a) Six chiral centres with nucleus i.e., 5, 8, 9, 10, 13 and 14.
- (b) Seven chiral centres with nucleus i.e., 3, 8, 9, 10, 11, 12, and 14.
- (c) Six chiral centers with nucleus i.e., 3, 8, 9, 10, 11, and 12.
- (d) Six chiral centers with the nucleus, i.e., 5, 7, 9, 10, 13, and 16.
Answer- (a) Six chiral centres with nucleus i.e., 5, 8, 9, 10, 13 and 14.
27. Ehrich’s reagent is
- (a) Bismuth iodide solution
- (b) p-dimethyl aniline solution in alcohol
- (c) p-dimethyl amino benzaldehyde solution
- (d) p-dimethyl aniline solution in methanol
Answer- (c) p-dimethyl amino benzaldehyde solution
28. Rancidity of fat is due to
- (a) oxidation
- (b) saponification
- (c) hydrolysis
- (d) neutralization
Answer- (a) oxidation
29. Vinca alkaloids are isolated from:
- (a) Catharanthus roseus and contain indole and indoline moieties
- (b) Rosco elromogens and contain indole and indoline moieties
- (c) Catharanthus roseus and contain quinoline and quinaldine moieties
- (d) Catharanthus indicus and contain indole and quinoline moieties
- Answer-(a) Catharanthus roseus and contain indole and indoline moieties
29. Ascorbic acid exists in nature :
- (a) Only in a reduced form which has only biological activity
- (b) Only in an oxidized form which has only biological activity
- (c) In both reduced and the oxidized forms in the state of reversible equilibrium which has biological activity
- (d) None of the above
Answer- (c) In both reduced and the oxidized forms in the state of reversible equilibrium which has biological activity
30. The opium alkaloids in papaver somniferous is present as one of the following. Identify
- (a) Free alkaloids
- (b) As salt of citric acid
- (c) As the salt of meconic acid
- (d) None of these
Answer- (a) Free alkaloids
31. Volatile oil from lemon peels contain d-limonene which is
- (a) Phenyl propane derivative
- (b) Bicyclic monoterpene derivative
- (c) Monocyclic monoterpene derivative
- (d) Acyclic sesquiterpene derivative
Answer- (c) Monocyclic monoterpene derivative
32. Fructose on reaction with nitric acid gives
- (a) Glycolic and tartaric acid
- (b) Fructonic acid
- (c) Glycollic acid
- (d) Sorbic acid
Answer- (a) Glycolic and tartaric acid
33. Fructose on reduction with sodium borohydride gives
- (a) sorbitol
- (b) manniol
- (c) sorbitol and mannitol
- (d) fructol
Answer- (c) sorbitol and mannitol
34. Glucose and fructose react with phenylhydrazine to form osazone. This reaction conclude
- (a) configuration at C-1 and C-2 is the same
- (b) configuration at C-3 and C-5 is the same
- (c) configuration at C-6 is the same
- (d) None of the above
Answer- (b) configuration at C-3 and C-5 is the same
35. and mannose differ in the configuration only at
- (a) Terminal carbon atom
- (b) One asymmetric carbon atom
- (c) First carbon atom
- (d) Two asymmetric carbon atom
Answer- (b) One asymmetric carbon atom
36. Glucosamine on treatment with hydrochloric acid followed by zinc and acetic acid yield
- (a) mannose
- (b) fructose
- (c) arabinose
- (d) ribulose
Answer- (b) fructose
37. Two isomers of aldose sugar differ only in the configuration of the first carbon atom is called
- (a) epimer
- (b) stereoisomer
- (c) anomers
- (d) enantiomer
Answer- (a) epimer
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