Development of Urinary System MCQ Quiz | Embryology

Welcome to the Embryology quiz on the Development of the Urinary System. This quiz is specifically designed for MBBS students to test and reinforce their understanding of the intricate processes involved in the formation of the kidneys, ureters, bladder, and urethra. You will encounter 25 multiple-choice questions covering key topics such as the pronephros, mesonephros, and metanephros, the critical role of reciprocal induction between the ureteric bud and metanephric blastema, the ascent and rotation of the kidneys, and common congenital anomalies like horseshoe kidney and renal agenesis. After submitting your answers, you will receive your score immediately. Correct and incorrect answers will be highlighted for your review. You can also download all questions with their correct answers in a PDF format for offline study.

1. The definitive kidney, the metanephros, develops from which two primary embryonic structures?

2. The ureteric bud, which gives rise to the collecting system of the kidney, is an outgrowth of which structure?

3. The excretory units (nephrons) of the metanephric kidney are derived from the:

4. Which of the following structures is NOT derived from the ureteric bud?

5. The phenomenon where the ureteric bud and metanephric blastema mutually stimulate each other’s development is known as:

6. A horseshoe kidney is a congenital anomaly where the lower poles of the two kidneys fuse. Its ascent is typically halted by which structure?

7. The trigone of the urinary bladder is primarily formed by the incorporation of the caudal ends of which ducts?

8. The majority of the urinary bladder lining (epithelium) is derived from which germ layer?

9. A newborn presents with urine leaking from the umbilicus. This condition is most likely due to a patent:

10. What is the fate of the pronephros in humans?

11. In males, the mesonephric (Wolffian) duct gives rise to all of the following structures EXCEPT:

12. Potter sequence (syndrome) is characterized by a flattened facial appearance, limb deformities, and pulmonary hypoplasia, which result from:

13. During the ‘ascent of the kidneys’, the hilum of the kidney rotates from facing anteriorly to facing:

14. The gene WT1 is crucial for kidney development as it enables the metanephric blastema to:

15. Exstrophy of the bladder is a severe congenital anomaly resulting from a defect in the:

16. The cloaca is divided into the urogenital sinus and the anorectal canal by the:

17. Unilateral renal agenesis is most commonly caused by:

18. During their ascent, the kidneys receive their blood supply from successively higher branches of the aorta. What is the definitive arterial supply to the adult kidneys?

19. In females, remnants of the mesonephric (Wolffian) duct may persist as a:

20. Which part of the urogenital sinus forms the prostatic and membranous urethra in males?

21. The mesonephros, or the ‘intermediate kidney’, functions transiently during which period of gestation?

22. Autosomal Recessive Polycystic Kidney Disease (ARPKD) is characterized by cysts forming primarily in which part of the nephron?

23. The molecular signal from the metanephric blastema that induces the outgrowth of the ureteric bud is:

24. What is the correct sequence of the three kidney systems that develop in the human embryo?

25. The final position of the kidneys in the adult is retroperitoneal, at approximately which vertebral levels?